Which adverse effect is commonly associated with SSRI antidepressants?

Which adverse effect is commonly associated with SSRI antidepressants?

• A. Weight gain
• B. Drowsiness
• C. Sexual dysfunction
• D. Hypertension

Answer: (C)

SSRIs frequently cause sexual dysfunction because increasing serotonin in the brain can interfere with the sexual response cycle, reducing libido, arousal, and orgasm. This side effect is common across many SSRIs and often persistent, making it the most characteristic adverse effect of this class. Weight changes and drowsiness can occur with some SSRIs, but they are less universally reported, and hypertension is not typically linked to SSRIs. If sexual side effects arise, clinicians may adjust the dose, change the timing, switch to a different antidepressant (like one with fewer sexual side effects), or consider adjunctive strategies.

SSRIs frequently cause sexual dysfunction because increasing serotonin in the brain can interfere with the sexual response cycle, reducing libido, arousal, and orgasm. This side effect is common across many SSRIs and often persistent, making it the most characteristic adverse effect of this class. Weight changes and drowsiness can occur with some SSRIs, but they are less universally reported, and hypertension is not typically linked to SSRIs. If sexual side effects arise, clinicians may adjust the dose, change the timing, switch to a different antidepressant (like one with fewer sexual side effects), or consider adjunctive strategies.