In SIADH, which of the following would indicate fluid volume overload?

In SIADH, which of the following would indicate fluid volume overload?

• A. Weight loss with edema
• B. Weight gain with edema
• C. Weight gain without edema
• D. No weight change

Answer: (C)

In SIADH, there is excess water retention due to increased ADH, which raises total body water and dilutes serum sodium. The body often maintains normal extracellular fluid volume, so edema does not usually develop; this is why patients are typically euvolemic. You can see a gain in body weight from the extra water, but without edema. That combination—weight gain with no edema—best indicates fluid overload in this scenario. Edema would point to true extracellular fluid excess from other causes, while weight loss would imply volume depletion, and no weight change suggests normal hydration.

In SIADH, there is excess water retention due to increased ADH, which raises total body water and dilutes serum sodium. The body often maintains normal extracellular fluid volume, so edema does not usually develop; this is why patients are typically euvolemic. You can see a gain in body weight from the extra water, but without edema. That combination—weight gain with no edema—best indicates fluid overload in this scenario. Edema would point to true extracellular fluid excess from other causes, while weight loss would imply volume depletion, and no weight change suggests normal hydration.